Cml

cml

What does CML stand for?

The Philadelphia chromosome as seen by fluorescent in situ hybridization (FISH). Chronic myelogenous leukemia ( CML ), also known as chronic myeloid leukemia, is a cancer of the white blood cells.

What is the difference between chronic myelogenous leukemia and CML?

Chronic myelogenous leukemia. It is a form of leukemia characterized by the increased and unregulated growth of myeloid cells in the bone marrow and the accumulation of these cells in the blood. CML is a clonal bone marrow stem cell disorder in which a proliferation of mature granulocytes ( neutrophils, eosinophils and basophils)...

What is CML and how does it affect the body?

In CML, a genetic change takes place in an early (immature) version of myeloid cells -- the cells that make red blood cells, platelets, and most types of white blood cells (except lymphocytes). This change forms an abnormal gene called BCR-ABL, which turns the cell into a CML cell.

What is the basic principle of CML?

The basic principle of CML is that current from a constant current generator is steered between two alternate paths depending on whether a logic zero or logic one is being represented. Typically, the generator is connected to the two sources of a pair of differential FETs with the two paths being their two drains.

What is chronic myelogenous leukemia (CML)?

Overview Chronic myelogenous leukemia (CML) is an uncommon type of cancer of the bone marrow — the spongy tissue inside bones where blood cells are made. CML causes an increased number of white blood cells in the blood.

What is capital market line (CML)?

Key Takeaways 1 The capital market line (CML) represents portfolios that optimally combine risk and return. 2 CML is a special case of the CAL where the risk portfolio is the market portfolio. ... 3 The intercept point of CML and efficient frontier would result in the most efficient portfolio called the tangency portfolio. More items...

What is the difference between the CML and SML?

The SML is derived from the CML. While the CML shows the rates of return for a specific portfolio, the SML represents the market’s risk and return at a given time, and shows the expected returns of individual assets.

What is the difference between CML and CAPM?

Under CAPM, all investors will choose a position on the capital market line, in equilibrium, by borrowing or lending at the risk-free rate, since this maximizes return for a given level of risk. The capital market line (CML) represents portfolios that optimally combine risk and return.

What is the difference between CML and blood cells?

Every blood cell grows from a stem cell in the bone marrow. Normally, the stem cells make an early stage of the blood cell called a blast. These blasts develop into healthy blood cells. myeloid stem cells – make red blood cells, platelets and all other types of white blood cell. CML is a cancer of the white blood cells.

How does CML affect the bone marrow?

In CML the bone marrow produces too many white cells, called granulocytes. These cells (sometimes called blasts or leukaemic blasts) gradually crowd the bone marrow, interfering with normal blood cell production. They also spill out of the bone marrow and circulate around the body in the bloodstream.

What are the signs and symptoms of CML?

This is because there are leukaemia cells building up in the bone marrow, increasing pressure on nerves and causing pain. Abnormal white blood cells collecting in the lymph glands may cause swelling. These symptoms may occur but are usually in the later stages of CML.

What is chronic myeloid leukaemia (CML)?

Chronic myeloid leukaemia (also called CML or CML leukemia) is a rare type of cancer. It causes the body to make too many white blood cells.

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